Studies on Germfree Hand-Forced Feeding and Germfree Reproduction in Rats

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Bilirubin and Urobilins in Germfree, Ex-germfree, and Conventional Rats

No urobilinogens are present in the feces or urine of germfree rats. After contamination of germfree animals with feces from conventional animals the exgermfree rats produced urobilins to the same extent as conventional animals on the same diet. The negative urobilin test turned positive in germfree animals infected with a single Clostridium-like microorganism isolated from the intestinal conte...

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Urinary Calculi in Germfree Rats

In a colony of germfree rats 50 per cent of the males had urinary calculi composed of calcium citrate and calcium oxalate. Genetically closely related conventional animals on the same sterilized diet did not present a single case of stone formation. The tendency to calculus formation disappeared when germfree animals were contaminated with the intestinal flora from conventional rats. The calcul...

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Hemorrhagic shock of germfree rats’

MCNULTY, Mr. P., JR. AND RAFAEL LINARES. Hemorrhagic shock ofgermfree rats. Am. J. Physiol. Ig8( I) : 141-144. 1g6o.Germfree and ordinarv laboratory rats of the same strain, half of each sort treated with oral aureomycin for 3 days prior to shock, were subjected to hemorrhagic shock. At the level and duration of hypotension selected, the procedure was highly lethal for all four groups. The sing...

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Irreversible Hemorrhagic Shock in Germfree Rats

Evidence has been provided that a state of irreversible hemorrhagic shock can be induced in a bacteria-free environment in rats reared under germfree conditions. The response to bleeding, the duration of the hypotensive episode and the pathological changes were the same in the germfree and in normal stock rats. The findings are interpreted as evidence opposed to the concept that bacteria or bac...

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Mucus in Intestinal Contents of Germfree Rats

The fecal excretion of total nitrogen and of total hexosamines has been determined in germfree and conventional rats. Germfree rats excreted more hexosamines than the conventional rats, while no difference in the nitrogen excretion was found. Infection of the germfree rats with a normal flora resulted in a temporarily increased excretion of hexosamines and nitrogen over a period of 2 to 3 days ...

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ژورنال

عنوان ژورنال: Eiyo To Shokuryo

سال: 1970

ISSN: 1883-8863

DOI: 10.4327/jsnfs1949.23.51